问题描述： 在ASP.NET中使用GridView控件展示数据，并且允许用户进行编辑和更新操作。但是在保存更改到数据库时，发现无法成功保存。

解决方法：

1. 确保GridView控件的EnableEditing、EnableUpdating和EnableDeleting属性设置为true。

    ...

2. 确保GridView控件的OnRowUpdating、OnRowDeleting和OnRowEditing事件与对应的事件处理程序绑定。

    ...

3. 在对应的事件处理程序中实现保存更改到数据库的逻辑。

protected void GridView1_RowUpdating(object sender, GridViewUpdateEventArgs e)
{
    GridViewRow row = GridView1.Rows[e.RowIndex];
    int id = Convert.ToInt32(GridView1.DataKeys[e.RowIndex].Value);
    string name = ((TextBox)row.FindControl("txtName")).Text;
    string email = ((TextBox)row.FindControl("txtEmail")).Text;

    // 保存更改到数据库
    string connectionString = ConfigurationManager.ConnectionStrings["ConnectionString"].ConnectionString;
    using (SqlConnection connection = new SqlConnection(connectionString))
    {
        string query = "UPDATE Users SET Name = @Name, Email = @Email WHERE ID = @ID";
        SqlCommand command = new SqlCommand(query, connection);
        command.Parameters.AddWithValue("@Name", name);
        command.Parameters.AddWithValue("@Email", email);
        command.Parameters.AddWithValue("@ID", id);

        connection.Open();
        command.ExecuteNonQuery();
    }

    GridView1.EditIndex = -1;
    GridView1.DataBind();
}

protected void GridView1_RowDeleting(object sender, GridViewDeleteEventArgs e)
{
    int id = Convert.ToInt32(GridView1.DataKeys[e.RowIndex].Value);

    // 从数据库中删除记录
    string connectionString = ConfigurationManager.ConnectionStrings["ConnectionString"].ConnectionString;
    using (SqlConnection connection = new SqlConnection(connectionString))
    {
        string query = "DELETE FROM Users WHERE ID = @ID";
        SqlCommand command = new SqlCommand(query, connection);
        command.Parameters.AddWithValue("@ID", id);

        connection.Open();
        command.ExecuteNonQuery();
    }

    GridView1.EditIndex = -1;
    GridView1.DataBind();
}

protected void GridView1_RowEditing(object sender, GridViewEditEventArgs e)
{
    GridView1.EditIndex = e.NewEditIndex;
    GridView1.DataBind();
}

在以上代码示例中，我们使用了SqlDataSource控件来绑定GridView控件的数据源，并在事件处理程序中执行数据库操作。你可以根据自己的具体需求和数据库结构进行相应的修改。