AWS S3 对上传的文件大小有限制，如果你上传的文件大于限制的大小，那么会抛出一个错误。如果你想解决这个问题，可以通过以下方法实现：

1. 修改文件上传大小限制的配置参数：

import boto3
from botocore.config import Config

AWS_ACCESS_KEY_ID = 'your_access_key_here'
AWS_SECRET_ACCESS_KEY = 'your_secret_access_key_here'
AWS_DEFAULT_REGION = 'your_default_region_here'
MAX_SIZE_MB = 50 # 限制上传大小为50MB

s3 = boto3.client(
    's3', 
    aws_access_key_id=AWS_ACCESS_KEY_ID,
    aws_secret_access_key=AWS_SECRET_ACCESS_KEY,
    region_name=AWS_DEFAULT_REGION,
    config=Config(signature_version='s3v4',
                  max_pool_connections=10,
                  retries=dict(max_attempts=10))
)

def upload_file_to_s3(file_path, bucket_name, file_key):
    file_size = os.path.getsize(file_path)
    if (file_size/1024/1024) > MAX_SIZE_MB:
        raise ValueError(f"文件过大，不能超过 {MAX_SIZE_MB} MB")

    with open(file_path, 'rb') as file_data:
        s3.upload_fileobj(file_data, bucket_name, file_key)

if __name__ == '__main__':
    upload_file_to_s3('myfile.jpg', 'mybucket', 'myfolder/myfile.jpg')

2. 使用 AWS S3 Multipart Upload，上传文件分成小块上传：

import boto3
import os
from boto3.s3.transfer import TransferConfig

AWS_ACCESS_KEY_ID = 'your_access_key_here'
AWS_SECRET_ACCESS_KEY = 'your_secret_access_key_here'
AWS_DEFAULT_REGION = 'your_default_region_here'
MAX_SIZE_MB = 50 # 限制上传大小为50MB

s3 = boto3.client(
    's3', 
    aws_access_key_id=AWS_ACCESS_KEY_ID,
    aws_secret_access_key=AWS_SECRET_ACCESS_KEY,
    region_name=AWS_DEFAULT_REGION
)

# 通过分块上传，限制上传大小
def multipart_upload(bucket_name, file_key, file_path):
    config = TransferConfig(
        multipart_threshold=1024 * 1024 * MAX_SIZE_MB,
        max_concurrency=10,
        multipart_chunksize=1024 * 1024 * 5,
        use_threads=True
    )

    s3.upload_file(
        file_path, 
        bucket_name, 
        file_key,
        Config=config
    )

if __name__ == '__main__':
    multipart_upload('mybucket', 'myfolder/myfile.jpg', 'myfile.jpg')
``